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PKG1 alpha, active 250ug

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货号：14-688M

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-688
Brand Family Upstate
Trade Name
  • Upstate
Description PKG1α Protein, active, 10 µg
Overview N-terminal 6His-tagged, recombinant, full length PKG1α.
References
Product Information
Applications
Application Active, N-terminal 6His-tagged, recombinant, full length PKG1α. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source PKG1α, expressed by baculovirus in Sf21 cells.
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • PRKG1
  • cGKI-beta
  • FLJ36117
  • PGK
  • PRKGR1A
  • cGKI-alpha
  • cGKI
  • MGC71944
  • OTTHUMP00000061216
  • CGKI
  • PRKG1B
  • cGKI-BETA
  • PRKGR1B
  • DKFZp686K042
Protein Target PKG1α
Purification Method Ni2+/NTA-agarose
Target Sub-Family AGC
UniProt Number
UniProt Summary SIZE: 686 amino acids; 77804 Da
SUBUNIT: Antiparallel homodimer. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1 (By similarity). Interacts with MRVI1.
DOMAIN: SwissProt: P14619
SIMILARITY: SwissProt: P14619 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. | Q13976 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain.
MISCELLANEOUS: Exhibit a substrate specificity similar but not identical to that of CAK.
Molecular Weight 80kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C from date of shipment
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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