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Qiagen 凯杰 Biosharp Omega

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12-Neural Cell Adhesion Molecule L1 (L1CAM) Beads - Magnetic

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货号：HL1CAM-MAG

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, R WB, IH(P) Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number ABT143
Description Anti-L1CAM Antibody
Alternate Names
  • Neural cell adhesion molecule L1
  • N-CAM-L1
  • NCAM-L1
  • CD171
Background Information Families of adhesion molecules which share common carbohydrate domains do exist, despite the structural and functional diversity of these glycoproteins. These include the Ca2+-independent neural adhesion molecules (N-CAM), myelin associated glycoprotein (MAG) and L1. L1 is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts.
References
Product Information
Format Affinity Purified
Control
  • Human brain tissue lysate
Presentation Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application Anti-L1CAM Antibody is a highly specific rabbit polyclonal antibody, that targets Neural cell adhesion molecule L1 & has been tested in western blotting & IHC (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application Notes Western Blotting Analysis: 0.4 µg/mL from a representative lot detected L1CAM in 10 µg of rat brain tissue lysate.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected L1CAM in human kidney and human cerebellum tissue.
Biological Information
Immunogen GST-tagged recombinant protein corresponding to the extracellular domain of human L1CAM.
Epitope Extracellular domain
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Specificity This antibody recognizes the extracellular domain of L1CAM in addition antibody recognizes the full length form (~220 kDa) and the cleaved form (~140 kDa) of L1CAM.
Species Reactivity
  • Human
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • L1CAM
  • CAML1
  • MIC5
Purification Method Affinity Purfied
UniProt Number
Molecular Weight ~220 / 140 kDa observed. The full length protein and the cleaved form of L1CAM have been observed at ~220 kDa and ~140 kDa, respectively (Kalus, I., et al. (2003). The Journal of Biological Chemistry. 278(12):10381-10388). Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 0.4 µg/mL of this antibody detected L1CAM in 10 µg of human brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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