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MilliplexMAP 9-Plex Multi-Pathway Magnetic Bead Signaling Kit

市场价：
23.00
促销价：
¥0.00

货号：48-680MAG

品牌：Millipore 密理博

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Replacement Information

重要规格表

Analytes Available Species Reactivity Key Applications Detection Methods
CREB (pS133), ERK (pT185/pY187), NFκB (pS536), JNK (pT183/pY185), p38 (pT180/pY182), p70 S6K (pT412), STAT3 (pS727), STAT5A/B (pY694/699), Akt (pS473) H Mplex Luminex xMAP
Description
Catalogue Number 48-680MAG
Trade Name
  • MILLIPLEX
Description MILLIPLEX MAP Multi-Pathway Magnetic Bead 9-Plex - Cell Signaling Multiplex Assay
Overview The MILLIPLEX® MAP 9-plex Multi-Pathway Signaling Magnetic Bead kit, phosphoprotein, is used to detect changes in phosphorylated ERK/MAP kinase 1/2 (Thr185/Tyr187), Akt (Ser473), STAT3 (Ser727), JNK (Thr183/Tyr185), p70 S6 kinase (Thr412), NFkB (Ser536), STAT5A/B (Tyr694/699), CREB (Ser133), and p38 (Thr180/Tyr182) in cell lysates using the Luminex® xMAP® technology. The detection assay is a rapid, convenient alternative to Western Blotting and immunoprecipitation procedures. Each kit has sufficient reagents for one 96-well plate assay.

References:
Pharmacol Res. 2016 Sep 12;113(Pt A):356-363. doi: 10.1016/j.phrs.2016.08.028. [Epub ahead of print]
The endocannabinoid anandamide causes endothelium-dependent vasorelaxation in human mesenteric arteries.
Stanley CP, Hind WH, Tufarelli C, O'Sullivan SE.

PLoS One. 2015 Sep 28;10(9):e0136546. doi: 10.1371/journal.pone.0136546. eCollection 2015.
The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation.
Smith M, Wilson R, O'Brien S, Tufarelli C, Anderson SI, O'Sullivan SE.

Cardiovasc Res. 2015 Sep 1;107(4):568-78. doi: 10.1093/cvr/cvv179. Epub 2015 Jun 19.
Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation.
Stanley CP, Hind WH, Tufarelli C, O'Sullivan SE.
References
Product Information
Detection method Luminex xMAP
Configuration Premixed
Panel Type Cell Signaling
Applications
Application Analyze a cell signaling panel using this kit. The analytes available for the cell signaling multiplex assay kit are: CREB (pS133), ERK (pT185/pY187), NFκB (pS536), JNK (pT183/pY185), p38 (pT180/pY182), p70 S6K (pT412), STAT3 (pS727), STAT5A/B (pY694/699), Akt (pS473).
Key Applications
  • Multiplexing
Biological Information
Specificity Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Species Reactivity
  • Human
Analytes Available
  • CREB (pS133)
  • ERK (pT185/pY187)
  • NFκB (pS536)
  • JNK (pT183/pY185)
  • p38 (pT180/pY182)
  • p70 S6K (pT412)
  • STAT3 (pS727)
  • STAT5A/B (pY694/699)
  • Akt (pS473)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Recommended storage for kit components is 2 - 8°C
Packaging Information
Material Size 96-well plate
Transport Information
Supplemental Information
Specifications

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