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Qiagen 凯杰 Biosharp Omega

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Anti-Rap1, clone 4C8/1

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号:05-911

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M WB M Purified Monoclonal Antibody
Description
Catalogue Number 05-911
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-RAP1 Antibody, clone 4C8/1
References
Product Information
Format Purified
Applications
Application Anti-RAP1 Antibody, clone 4C8/1 is a high quality Mouse Monoclonal Antibody for the detection of RAP1 & has been validated in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogen Human Rap1 Clone 4C8/1
Clone clone 4C8/1
Host Mouse
Specificity Rap1
Isotype IgG2b
Species Reactivity
  • Human
  • Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TERF2IP
  • hRap1
  • DRIP5
  • RAP1
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q9NYB0 # May play a role in telomere length regulation.
SIZE: 399 amino acids; 44260 Da
SUBUNIT: Homodimer. Binds to TRF2 (but not TRF1) with its C- terminus.
SUBCELLULAR LOCATION: Nucleus. Note=Colocalizes with telomeric DNA in interphase and metaphase cells.
TISSUE SPECIFICITY: Ubiquitous. Highly expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: Q9NYB0 ## Contains 1 BRCT domain. & Contains 1 Myb-like domain.
MISCELLANEOUS: Recruited to telomeres by TRF2; seemingly it does not directly bind to DNA itself.
Molecular Weight Mr 50kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on HeLa nuclear extracts
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions stable 2 years at -20°C from date of shipment
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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