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Qiagen 凯杰 Biosharp Omega

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PIP4-Kinase HTRF Assay (1920 wells)

市场价：
105.00
促销价：
¥0.00

货号：33-055

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 33-055
Brand Family Upstate
Trade Name
  • HTRF
  • Upstate
Description PIP4-Kinase HTRF Assay
References
Product Information
Components
  • Reaction Buffer (4X)
  • DM A Detection Reagent
  • DM C Detection Reagent
  • DM E Detection Reagent
  • Phosphatidylinositol 5-phosphate (1mM)
  • Phosphatidylserine (1mM)
  • Stop Reagent D
Detection method HTRF
Applications
Application The PIP4 Kinase HTRF Assay kit provides a method for assaying PI(5)P-4 kinases in a homogenous 1920 well format. Suitable for screening of potential inhibitors of these enzymes.
Key Applications
  • Kinase Assay
Biological Information
Species Reactivity
  • Human
  • Mouse
Analytes Available
  • PIP4 Kinase
Entrez Gene Number
Entrez Gene Summary Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
Gene Symbol
  • PIP4K2α
Target Sub-Family PI3K/PI4K
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 12 months at -70°C
Packaging Information
Material Size 1920 wells
Material Package Kit capacity: 1920 wells
Transport Information
Supplemental Information
Specifications

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