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Anti-GLUT-5, a.a. 490-502 (rabbit polyclonal)

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货号：07-1406

品牌：Millipore 密理博

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Replacement Information

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R, M, Gp WB Rb Serum Polyclonal Antibody
Description
Catalogue Number 07-1406
Replaces AB1348
Description Anti-GLUT-5 Antibody, a.a. 490-502
Alternate Names
  • Fructose transporter
  • Glucose transporter type 5, small intestine
  • glucose transporter-like protein 5
  • solute carrier family 2 (facilitated glucose transporter),
    member 5
  • solute carrier family 2 (facilitated glucose/fructose
    transporter), member 5
Background Information A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.
References
Product Information
Format Serum
Control
  • Mouse kidney lysate.
Presentation Liquid containing 0.05% sodium azide.
Applications
Application Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogen Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.
Epitope C-terminus
Host Rabbit
Specificity Recognizes GLUT-5.
Species Reactivity
  • Rat
  • Mouse
  • Guinea Pig
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • GLUT-5
  • GLUT5
  • OTTHUMP00000001704
Purification Method Unpurified rabbit serum
UniProt Number
UniProt Summary FUNCTION: Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
INDUCTION: By forskolin (in Caco-2 cells).
SEQUENCE SIMILARITIES: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. [View classification]
MASS SPECTROMETRY: Molecular mass is 54973.98 Da from positions 1 - 501. Determined by MALDI.
SEQUENCE CAUTION: The sequence AAB60641.1 differs from that shown. Reason: Erroneous gene model prediction.
Molecular Weight Approx. 54 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.
Packaging Information
Material Size 50 µL
Transport Information
Supplemental Information
Specifications

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