Anti-Gia 1-2 (Rabbit Polyclonal IgG) - 炼石商城

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Anti-Gia 1-2 (Rabbit Polyclonal IgG)

市场价：: 0.00

促销价：: ¥0.00

货号：06-236

品牌：Millipore 密理博

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北京朝阳

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
B, H, M, R	ICC, IP, WB	Rb	Purified	Polyclonal Antibody

Description
Catalogue Number	06-236
Brand Family	Upstate
Trade Name	Upstate
Description	Anti-Giα1/2 Antibody

References

Product Information
Format	Purified
Control	Widely expressed
Presentation	A diluted rabbit serum in PBS (50 mM KHPO4, 140 mM NaCl). Frozen solution

Applications
Application	Detect Giα1/2 using this Anti-Giα1/2 Antibody validated for use in IC, IP & WB.
Key Applications	Immunocytochemistry Immunoprecipitation Western Blotting

Biological Information
Immunogen	10 residue synthetic peptide (KNNLKDCGLF) corresponding to the c-terminus of Gia1 and Gia2
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	Recognizes Giα1 and Giα2.
Isotype	IgG
Species Reactivity	Bovine Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_002069
Entrez Gene Summary	Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM]
Gene Symbol	GNAI1 Gi
UniProt Number	P63096
UniProt Summary	FUNCTION: SwissProt: P63096 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. SIZE: 354 amino acids; 40361 Da SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity). SIMILARITY: SwissProt: P63096 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Molecular Weight	40 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	routinely evaluated by immunoblot on Rat Brain Microsomal Preparation or solubilized plasma membranes from mouse 3T3/A31 fibroblasts
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	50 µL

Transport Information

Supplemental Information

Specifications

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