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Rb Anti-Aquaporin 7

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号:AB15568-200UL

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M, R ICC, IHC, WB Rb Purified Polyclonal Antibody
Description
Catalogue Number AB15568-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Aquaporin 7 Antibody
Alternate Names
  • AQP7
References
Product Information
Format Purified
Control
  • Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
Presentation Lyophilized from phosphate buffered saline, pH 7.4 and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Applications
Application Anti-Aquaporin 7 Antibody is an antibody against Aquaporin 7 for use in IC, IH & WB.
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blotting
Application Notes Western blot: 1:200-1:600 using ECL on rat and mouse kidney membrane lysate.
Immunohistochemistry on rat testis sections.
Immunocytochemistry: 1:800 using 3T3-L1 adipocytes.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Purified peptide from the N-terminus of rat AQP7 (Accession number P56403).
Host Rabbit
Species Reactivity
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.
Gene Symbol
  • AQP7
  • Aquaporin-7-like
  • AQP-7
  • AQPap
  • AQP9
  • MGC149555
  • Aquaporin-7
  • MGC149556
  • AQP7L
Purification Method ImmunoAffinity Purified
UniProt Number
UniProt Summary FUNCTION: SwissProt: O14520 # Forms a channel for water and glycerol.
SIZE: 342 amino acids; 37232 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
DOMAIN: SwissProt: O14520 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA).
SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 200 µL
Transport Information
Supplemental Information
Specifications

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