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Rb X Bovine Perilipin A

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货号：AB10200

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
B, M WB Rb Purified Polyclonal Antibody
Description
Catalogue Number AB10200
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Perilipin A Antibody
Background Information Perilipin A is the predominant isoform of perilipins a family of proteins which are the most abundant proteins at the surfaces of lipid droplets in adipocytes and are also found in steroidogenic cells.
References
Product Information
Format Purified
Presentation Purified immunoglobulin presented as a liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing protease free bovine serum albumin.
Applications
Application Detect Perilipin A using this Anti-Perilipin A Antibody validated for use in WB.
Key Applications
  • Western Blotting
Application Notes Suggested dilutions:
Western Blot: 0.1-0.2 μg/mL
Biological Information
Immunogen Bovine Perilipin A
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rabbit
Species Reactivity
  • Bovine
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis.
Gene Symbol
  • PLIN
  • PERI
  • Perilipin
  • perilipin
UniProt Number
UniProt Summary FUNCTION: SwissProt: O60240 # Modulator of adipocyte lipid metabolism, it coats lipid storage droplets to protect them to be broken down by hormone- sensitive lipase (HSL). Its absence may result in leanness.
SIZE: 522 amino acids; 55950 Da
SUBUNIT: Interacts with ABHD5 (By similarity).
SUBCELLULAR LOCATION: Lipid droplet (By similarity). Note=Lipid droplet surface-associated (By similarity).
TISSUE SPECIFICITY: Adipocytes.
PTM: Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity).
SIMILARITY: SwissProt: O60240 ## Belongs to the perilipin family.
Molecular Weight 64kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by immunoblot.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain frozen at -20C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze-thaw cycles.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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