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Anti-Rab13 (rabbit polyclonal)

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号:07-794

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, R WB, IP, IF Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number 07-794
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Rab13 Antibody
Background Information Rab proteins are members of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in vesicle trafficking and it is believed that a different Rab protein may be needed for each step of the vesicular transport. It is thought Rab4 and Rab11 are involved in internalization, sorting, and transport to lysosomes or recycling, of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2, or the H+/K+ ATPase.
References
Product Information
Format Affinity Purified
Control
  • PC12 Cell Lysate
Presentation Affinity Purified rabbit IgG in storage buffer containing tri-citrate-phosphate, pH 7-8 and 0.1% sodium azide.
Applications
Application Detect Rab13 using this Anti-Rab13 Antibody validated for use in WB, IP & IF.
Key Applications
  • Western Blotting
  • Immunoprecipitation
  • Immunofluorescence
Application Notes Immunofluorescence Staining:
Independent laboratory demonstrated this antibody worked in Immunofluorescence studies at a 1:100-1:500 dilution.

Immunoprecipitation (IP):
Independent laboratory demonstrated this antibody works in Immunoprecipitation.
Biological Information
Immunogen Sythnetic peptide of amno acids 129-148 of rat Rab13
Host Rabbit
Specificity Recognizes Rab13
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Rab13
  • RAB13, member RAS oncogene family
  • GIG4
  • growth-inhibiting gene 4 protein
UniProt Number
UniProt Summary FUNCTION: Could participate in polarized transport, in the assembly and/or the activity of tight junctions.
SIZE: 203 amino acids; 22,774 Da
SUBCELLULAR LOCATION:Cell junction › tight junction. Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Note= Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions.
TISSUE SPECIFICITY: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.
SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
Molecular Weight 25 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Western Blot Analysis:
This lot detected Rab13 at 1:1,000 (1g/mL) dilution in lysates from PC12 lysate resolved via SDS-PAGE and transferred to PVDF (Immobilon-P).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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