Anti-Sox4 (rabbit polyclonal) - 炼石商城

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Anti-Sox4 (rabbit polyclonal)

市场价：: 0.00

促销价：: ¥0.00

货号：AB10537

品牌：Millipore 密理博

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北京朝阳

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
M	IHC	Rb	Serum	Polyclonal Antibody

Description
Catalogue Number	AB10537
Description	Anti-Sox4 Antibody
Alternate Names	SRY (sex determining region Y)-box 4 ecotropic viral integration site 16 SRY-related HMG-box gene 4 SRY-box containing gene 4
Background Information	Sox4 is a protein transcription factor belonging to a family of transcription factors consisting of well over 14 members and 7 different subgroups. Members of the Sox family are characterized by DNA binding domains showing strong similarity to HMG box domains. Proteins belonging to the Sox family are involved in various phases of embryonic development including; neural development, hemopoiesis, lens development, chondrogenesis, and sex determination as well as cell fate. Sox4 is a part of the C subgroup of Sox proteins, and is involved in B cell and endocardial ridge development. During embryonic development, Sox4 expression has been observed in several tissues including; lung, gonads, embryonic heart, mesonephros, CNS, thymus, tooth buds, and T and pre-B cells. Sox4 has also been observed in mature tissue, especially in the pancreas, heart, lung, CHS, thymus, and gonads. Recent studies have linked overexpression of Sox4 to the development of various types of tumors and cancers, and indicating a potential for Sox4 as a therapeutic marker.

References

Product Information
Format	Serum
Control	Mouse embryo pancreas tissue
Presentation	Rabbit polyclonal serum containing 0.05% sodium azide.

Applications
Application	Use Anti-Sox4 Antibody (Rabbit Polyclonal Antibody) validated in IHC to detect Sox4 also known as SRY (sex determining region Y)-box 4, ecotropic viral integration site 16.
Key Applications	Immunohistochemistry
Application Notes	Western Blotting: Using 1:1000 dilution of a representative lot of this antibody and lysate of human pancreas, a faint band was observed at ~48 kDa with a stronger uncharacterized band observed at ~38 kDa.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to mouse Sox4.
Host	Rabbit
Specificity	This antibody recognizes Sox4.
Species Reactivity	Mouse
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NP_033264
Gene Symbol	SOX4 EVI16
Purification Method	Unpurified
UniProt Number	Q5SW95
Molecular Weight	Calculated MW ~45 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Immunohistochemistry in mouse embryo pancreas tissue. Immunohistochemistry Analysis: 1:300 dilution of this antibody detected Sox4 in mouse embryo pancreas tissue.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

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