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Anti-Phosphatidylserine, clone 1H6 (mouse monoclonal)

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货号：16-256

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
Vrt FC M AlexaFluor®488 Monoclonal Antibody
Description
Catalogue Number 16-256
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Phosphatidylserine Antibody, clone 1H6, Alexa Fluor® 488
Overview Significance:
Anti-Phosphatidylserine may be used to detect translocation of the membrane phospholipid phosphatidylserine (PS) from the inner to the outer cell membrane leaflet; it provides an alternative to Annexin V for quantitation of apoptosis.
Background Information Phosphatidylserine, or PS, is a naturally occurring, phospholipid nutrient. PS is essential to the functioning of all the cells of the body, but is most concentrated in the brain. Its relative abundance in this organ reflects its proven involvement in an assortment of nerve cell functions, including nerve transmitter release and synaptic activity. Clinical studies have suggested that PS can support brain functions that tend to decline with age.
References
Product Information
Format AlexaFluor®488
Control
  • Staurosporine treated Jurkat cells.
    Included Negative Control: Catalog # 16-240, Alexa Fluor® 488-conjugated Normal Mouse IgG.
Presentation Purified mouse monoclonal IgG in buffer containing PBS containing 1% BSA, 0.05% Tween, 0.05% sodium azide. Liquid at 4ºC.
Applications
Application Detect Phosphatidylserine using this Anti-Phosphatidylserine Antibody, clone 1H6, Alexa Fluor 488 validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
Immunogen Liposomes containing 70% phosphatidylserine and 30% phosphatidylglycerol.
Clone clone 1H6
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Recognizes phosphatidylserine (PS) in cell membranes.
Isotype IgG
Species Reactivity
  • Vertebrates
Antibody Type Monoclonal Antibody
Modifications
  • Phosphorylation
Purification Method Protein G Purified
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Flow Cytometry: 0.2 μg of this antibody detected Phosphatidylserine in fixed Jurkat cells (see page 2).

Apoptosis Assay: Time course for induction of apoptosis in Jurkat cells by staurosporine, measured using either an Anti-Phosphatidylserine, clone 1H6, Alexa Fluor® 488 conjugate or an Annexin V FITC conjugate.
Usage Statement
  • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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