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Milli-Mark™ Anti-CD64-PE, clone 10.1

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货号：FCMAB203P

品牌：Millipore 密理博

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Replacement Information

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H FC M Phycoerythrin Monoclonal Antibody
Description
Catalogue Number FCMAB203P
Trade Name
  • Milli-Mark
Description Milli-Mark™ Anti-CD64-PE Antibody, clone 10.1
Alternate Names
  • High affinity immunoglobulin gamma Fc receptor I
  • IgG Fc receptor I
  • Fc-gamma RIA
  • FcgammaRIa
  • Fc-gamma RI
  • FcRI
Background Information CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG1>IgG3>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).
References
Product Information
Format Phycoerythrin
Control
  • PBMC's
Presentation Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Applications
Application Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
Immunogen Human rheumatoid synovial fluid cells and monocytes.
Clone 10.1
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Antibody recognizes Human CD64 antigen.
Isotype IgG1κ
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Purification Method Protein A Purfied
UniProt Number
Molecular Weight 72 kDa (Sun W, 1997)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by flow cytometry using human PBMCs
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size 100 tests
Transport Information
Supplemental Information
Specifications

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