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Anti-IKKe

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货号：07-580

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M WB Rb Purified Polyclonal Antibody
Description
Catalogue Number 07-580
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-IKKε Antibody
References
Product Information
Format Purified
Presentation of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Applications
Application This Anti-IKKε Antibody is validated for use in WB for the detection of IKKε.
Key Applications
  • Western Blotting
Biological Information
Immunogen KLH-conjugated, synthetic peptide corresponding to amino acids 582-596 (SHLAKRLLQVFQEEC) of human IKKε
Host Rabbit
Specificity IKKε
Isotype IgG
Species Reactivity
  • Human
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • IKBKE
  • IKKI
  • MGC125294
  • IKK-i
  • IKKE
  • IKK-epsilon
  • IkBKE
  • MGC125295
  • MGC125297
  • KIAA0151
Purification Method Protein A Purfied
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q14164 # Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response.
SIZE: 716 amino acids; 80462 Da
SUBUNIT: May interact with MAVS/IPS1. Interacts with AZI2. Interacts with SIKE. Interacts with TICAM1/TRIF, IRF3 and DDX58/RIG-I, interactions are disrupted by the interaction between IKBKE and SIKE.
SUBCELLULAR LOCATION: Cytoplasm (Probable).
TISSUE SPECIFICITY: Highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon.
PTM: Autophosphorylated.
SIMILARITY: SwissProt: Q14164 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. IkappaB kinase subfamily. & Contains 1 protein kinase domain.
Molecular Weight Mr 80kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 2 years at -20°
Packaging Information
Material Size 200 µg
Transport Information
Supplemental Information
Specifications

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