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ARG, ACTIVE 10UG

市场价：: 0.00

促销价：: ¥0.00

货号：14-460

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

Description
Catalogue Number	14-460
Brand Family	Upstate
Trade Name	Upstate
Description	Arg Protein, active, 10 µg
Overview	N-terminal His6-tagged, recombinant amino acids, 27-end, mouse Arg

References

Product Information

Applications
Application	Active, N-terminal His6-tagged, recombinant amino acids, 27-end, mouse Arg, for use in Kinase Assays.
Key Applications	Kinase Assay

Biological Information
Source	expressed in Sf21 cells
Specific Activity	For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number	NM_005158.2 NM_007314.1
Entrez Gene Summary	The gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Gene Symbol	ABL2 Abelson-related ABLL ARG
Protein Target	Arg
Purification Method	Ni²⁺/NTA-agarose
Target Sub-Family	TK
UniProt Number	P42684
UniProt Summary	FUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. COFACTOR: Magnesium or manganese. SIZE: 1182 amino acids; 128343 Da SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Widely expressed. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight	124.5kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	routinely evaluated by phosphorylation of Abltide
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	6 months at -70°C

Packaging Information
Material Size	10 µg
Material Package	Also available in 250 µg size --call for pricing and availability and reference catalog number 14-460M when ordering the 250 µg size.

Transport Information

Supplemental Information

Specifications

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