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WNK3, active 250ug

价:
32.00
价:
¥0.00

号:14-658M

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information
Description
Catalogue Number 14-658M
Brand Family Upstate
Trade Name
  • Upstate
Description WNK3 Protein, active, 250 µg
Overview N-terminal 6His-tagged, recombinant, human WNK3, amino acids 1-434
References
Product Information
Applications
Application Active, N-terminal 6His-tagged, recombinant, human WNK3, amino acids 1-434, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source Expressed by baculovirus in Sf21 cells
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Entrez Gene Summary Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]
Gene Symbol
  • WNK3
  • KIAA1566
  • PRKWNK3
Protein Target WNK3
Purification Method Ni2+/NTA-agarose
Target Sub-Family STE
UniProt Number
UniProt Summary COFACTOR: Magnesium (By similarity).
SIZE: 1743 amino acids; 191789 Da
TISSUE SPECIFICITY: Expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney. Very low levels of expression were also detected in fetal heart, thymus, liver and spleen.
SIMILARITY: SwissProt: Q9BYP7 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. & Contains 1 protein kinase domain.
Molecular Weight 53.1kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by phosphorylation of MBP (#13-104).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C
Packaging Information
Material Size 250 µg
Material Package Also available in 10 μg size (cat#14-658) and in bulk (cat# 14-658-K).
Transport Information
Supplemental Information
Specifications

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