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Qiagen 凯杰 Biosharp Omega

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PhKg2, active 10ug

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货号：14-698

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-698
Brand Family Upstate
Trade Name
  • Upstate
Description PhKγ2 Protein, active, 10 µg
Overview GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L
References
Product Information
Applications
Application Active, GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source expressed in E. coli
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • PHKG2
  • PSK-C3
  • PHK-gamma-T
Protein Target PhKg2
Purification Method Glutathione-agarose
Target Sub-Family misc
UniProt Number
UniProt Summary FUNCTION: SwissProt: P15735 # Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. This isozyme may regulate glycogeneolysis in the testis.
SIZE: 406 amino acids; 46442 Da
SUBUNIT: Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.
DISEASE: SwissProt: P15735 # Defects in PHKG2 are a cause of glycogen storage disease type 9C (GSD9C) [MIM:172471]; also known as autosomal liver glycogenosis. GSD9C is a metabolic disorder manifesting in infancy with hepatomegaly, growth retardation, and elevated plasma aminotransferases and lipids.
SIMILARITY: SwissProt: P15735 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Molecular Weight 61.37kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by phosphorylation of ZIPtide (Catalog # 12-545)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C from date of shipment
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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