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Qiagen 凯杰 Biosharp Omega

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GRK5, active 10ug

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货号：14-714

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-714
Brand Family Upstate
Trade Name
  • Upstate
Description GRK5 Protein, active, 10 µg
Overview N-terminal 6His-tagged, recombinant, full length, human GRK5
References
Product Information
Applications
Application Active, N-terminal 6His-tagged, recombinant, full length, human GRK5, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source expressed by baculovirus in Sf21 cells
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene Summary This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
Gene Symbol
  • GRK5
  • GPRK5
Protein Target GRK5
Purification Method Ni2+/NTA-agarose
Target Sub-Family AGC
UniProt Number
UniProt Summary FUNCTION: SwissProt: P34947 # Specifically phosphorylates the activated forms of G protein-coupled receptors.
SIZE: 590 amino acids; 67787 Da
TISSUE SPECIFICITY: Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.
SIMILARITY: SwissProt: P34947 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
Molecular Weight 71.6kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by phosphorylation of casein
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C from date of shipment
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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