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VRK2, active

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货号：14-732

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-732
Trade Name
  • Upstate
Description VRK2, active
Overview VRK2 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This protein
is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis,
leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to
phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been
found for this gene.
References
Product Information
Presentation Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Applications
Key Applications
  • Kinase Assay
Biological Information
Source N-terminal 6His-tagged, recombinant, human VRK2 amino acids 1–336, expressed by baculovirus in Sf21 insect cells
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • VRK2
Purification Method Purified using Ni2+/NTA agarose.
Target Sub-Family CK1
UniProt Number
Molecular Weight 43 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by phosphorylation of casein
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C
Packaging Information
Material Size 10 µg
Material Package Also available in 250μg size as catalog # 14-732M and in bulk as catalog # 14-732-K.
Transport Information
Supplemental Information
Specifications

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