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Anti-Tyrosine Hydroxylase AP (chicken polyclonal)

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货号：AB9702

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M ICC, IHC, WB Ch Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB9702
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Tyrosine Hydroxylase Antibody
Alternate Names
  • TH
References
Product Information
Format Affinity Purified
Presentation Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
Applications
Application Anti-Tyrosine Hydroxylase Antibody is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blotting
Application Notes Immunohistochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed tissues.
Immunocytochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed cells.
Western Blotting: 1:2000-1:5000

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Synthetic peptides from human/mouse Tyrosine Hydroxylase
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Chicken
Specificity Recognizes Tyrosine Hydroxylase
Isotype IgY
Species Reactivity
  • Human
  • Mouse
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.
Gene Symbol
  • TH
  • TYH
  • EC 1.14.16.2
UniProt Number
UniProt Summary FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
COFACTOR: Fe(2+) ion.
SIZE: 528 amino acids; 58524 Da
TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Packaging Information
Material Size 500 µL
Transport Information
Supplemental Information
Specifications

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