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Qiagen 凯杰 Biosharp Omega

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A-DIMETH-HIS H3 (L9), BIOTIN 100UL

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号:16-187

牌:Millipore 密理博

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Replacement Information

重要规格表

Empirical Formula
C₉₆H₁₂₂N₁₈O₁₆

价格及供货情况

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681660-1MGCN
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      塑胶安瓿;塑胶针药瓶 1 mg
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      Description
      Overview A 14-amino acid cyclic peptide that potently blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-induced actin assembly in Xenopus egg cytoplasmic extract (IC50 ~ 2 µM). Shown to directly bind to neural Wiskott Aldrich syndrome protein (N-WASP) with high-affinity, and prevent the activation of actin-related protein 2/3 (Arp2/3) complex by inhibiting the interaction between N-WASP and Arp2/3.
      Catalogue Number 681660
      Brand Family Calbiochem®
      Synonyms cyclo(LKDFDPDFLFDPLQ)₂
      References
      References Peterson, J.R., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10624.
      Suetsugu, S., et al. 2001. J. Biol. Chem. 276, 33175.
      Product Information
      ATP Competitive N
      Form White lyophilized solid
      Formulation Supplied as a trifluoroacetate salt.
      Hill Formula C₉₆H₁₂₂N₁₈O₁₆
      Chemical formula C₉₆H₁₂₂N₁₈O₁₆
      Hygroscopic Hygroscopic
      Reversible N
      Applications
      Biological Information
      Primary Target Neural Wiskott Aldrich syndrome protein (N-WASP)
      Primary Target IC<sub>50</sub> ~ 2 µM blocking phosphatidylinositol 4,5-bisphosphate (PIP2)-induced actin assembly in Xenopus egg cytoplasmic extract
      Purity ≥95% by HPLC
      Physicochemical Information
      Cell permeable N
      Peptide Sequence cyclo(LLys-DPhe-DPro-DPhe-LPhe-DPro-LGln)₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

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