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Anti-Sec61 b

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货号：07-205

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
Ca, H IP, WB Rb Serum Polyclonal Antibody
Description
Catalogue Number 07-205
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-Sec61β Antibody
References
Product Information
Format Serum
Presentation antiserum containing 0.05% sodium azide and 30% glycerol
Applications
Application Anti-Sec61β Antibody detects level of Sec61β & has been published & validated for use in IP & WB.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Biological Information
Immunogen peptide conjugated to KLH corresponding to amino acids 2-10 of human Sec61β (PGPTPSGTN-C)
Host Rabbit
Specificity Sec61β
Isotype IgG
Species Reactivity
  • Canine
  • Human
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Gene Symbol
  • SEC61B
Purification Method Antiserum
UniProt Number
UniProt Summary FUNCTION: SwissProt: P60468 # Necessary for protein translocation in the endoplasmic reticulum.
SIZE: 96 amino acids; 9974 Da
SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61- beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62.
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein.
SIMILARITY: SwissProt: P60468 ## Belongs to the SEC61-beta family.
Molecular Weight 14kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on RIPA lysates from non-stimulated A431 cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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