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Anti-REA

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货号：07-234

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M, R IP, WB, ICC Rb Purified Polyclonal Antibody
Description
Catalogue Number 07-234
Brand Family Upstate
Trade Name
  • Upstate
Description Anti-REA Antibody
References
Product Information
Format Purified
Control
  • 3T3 nuclear extract
Presentation 200 μg of protein A purified rabbit IgG in 200 μL of 0.07 M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol.
Applications
Application Detect REA with Anti-REA Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP, WB, ICC.
Key Applications
  • Immunoprecipitation
  • Western Blotting
  • Immunocytochemistry
Biological Information
Immunogen His6-tagged fusion protein corresponding to amino acid residues 88-299 of mouse REA-1/BAP-37/prohibitin-related protein
Host Rabbit
Specificity REA
Isotype IgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PHB2
  • BCAP37
  • BAP
  • Prohibitin-2
  • REA
  • D-prohibitin
  • PNAS-141
  • MGC117268
  • p22
  • Bap37
Purification Method Protein A chromatography
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q99623 # Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
SIZE: 299 amino acids; 33296 Da
SUBUNIT: Interacts with PHB, ESR1, HDAC1 and HDAC5 (By similarity).
SUBCELLULAR LOCATION: Mitochondrion inner membrane (By similarity). Cytoplasm (By similarity). Nucleus (By similarity). Note=Also cytoplasmic and nuclear (By similarity).
DEVELOPMENTAL STAGE: Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
SIMILARITY: SwissProt: Q99623 ## Belongs to the prohibitin family.
Molecular Weight 37kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by immunoblot on 3T3 nuclear extract
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 2 years at -20°C
Packaging Information
Material Size 200 µg
Transport Information
Supplemental Information
Specifications

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