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Qiagen 凯杰 Biosharp Omega

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Anti-CD8a (human), APC, clone RPA-T8

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货号：MABF1666

品牌：Millipore 密理博

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Replacement Information

特卖

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, M FC Ht Purified Monoclonal Antibody
Description
Catalogue Number MABF116
Description Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157
Alternate Names
  • T-cell surface glycoprotein CD3 gamma chain
  • T-cell receptor T3 gamma chain
  • CD3g
  • HMT3-2
Background Information The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains: gamma, delta, epsilon and zeta. CD3 is first detectable in early thymocytes and one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, it is detected on the cell surface. The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies.
References
Product Information
Format Purified
Control
  • Jurkat cells
Presentation Purified armenian hamster monoclonal IgG2bλ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
Application Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157 detects level of CD3 gamma delta (HMT3-2) & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
Immunogen Purified protein corresponding to mouse CD3 gamma delta.
Clone Ham25-1157
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Hamster
Specificity This antibody recognizes CD3 gamma delta.
Species Reactivity
  • Human
  • Mouse
Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse based on 100% sequence homology.
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Cd3g
Purification Method Protein G Purified
UniProt Number
UniProt Summary FUNCTION: The CD3 complex mediates signal transduction.

SUBUNIT STRUCTURE: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Molecular Weight 21 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Flow Cytometry in Jurkat cells.

Flow Cytometry Analysis: 2.5 µg/mL of this antibody detected CD3 gamma delta in 1X10E5 Jurkat cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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