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Anti-CD3 (hu), violetFluor™ 450 cl UCHT1

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号:MABF1757

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB Rb Unpurified Monoclonal Antibody
Description
Catalogue Number MABF757
Description Anti-TFPI, clone EPR7941, Rabbit Monoclonal Antibody
Alternate Names
  • Tissue factor pathway inhibitor
  • TFPI
  • Extrinsic pathway inhibitor
  • EPI
  • Lipoprotein-associated coagulation inhibitor
  • LACI
  • TFPI
  • LACI
  • TFPI1
Background Information Tissue factor pathway inhibitor (TFPI), also known as Extrinsic pathway inhibitor or EPI or Lipoprotein-associated coagulation inhibitor or LACI, and encoded by the gene name TFPI or LACI or TFPI1, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. It is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
References
Product Information
Format Unpurified
Presentation Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
Applications
Application Anti-TFPI, clone EPR7941, Rabbit Monoclonal Antibody is an antibody against TFPI for use in Western Blotting.
Key Applications
  • Western Blotting
Application Notes Produced in collaboration with Epitomics™
Biological Information
Immunogen Synthetic peptide corresponding to the C-terminus of human TFPI.
Epitope C-terminus
Clone EPR7941
Concentration Please refer to lot specific datasheet.
Host Rabbit
Isotype IgG
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Gene Symbol
  • TFPI
  • LACI
  • TFPI1
Purification Method Unpurified
UniProt Number
Molecular Weight ~40 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blotting in HepG2, U-87 MG, Caco-2, and human placenta lysates.

Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected TFPI in HepG2, U-87 MG, Caco-2, and human placenta lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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