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Qiagen 凯杰 Biosharp Omega

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Anti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 (rat monoclonal)

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号:MABF1460

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M FC R redFluor™ 710 Monoclonal Antibody
Description
Catalogue Number MABF1460
Description Anti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody
Alternate Names
  • L-selectin
  • CD62 antigen-like family member L
  • Leukocyte adhesion molecule 1 (LAM-1)
  • Leukocyte-endothelial cell adhesion molecule 1 (LECAM1)
  • Lymph node homing receptor
  • Lymphocyte antigen 22 (Ly-22)
  • Lymphocyte surface MEL-14 antigen
  • CD62L
  • CD62L (L-Selectin)
Background Information The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
References
Product Information
Format redFluor™ 710
Presentation Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Applications
Application Anti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody is an antibody against CD62L for use in Flow Cytometry.
Key Applications
  • Flow Cytometry
Biological Information
Immunogen Immunogen information for this antibody is proprietary information.
Clone MEL-14
Concentration Please refer to lot specific datasheet.
Host Rat
Species Reactivity
  • Mouse
Antibody Type Monoclonal Antibody
Gene Symbol
  • Sell
  • Lnhr
  • Ly-22
  • Ly22
Purification Method Purified by size-exclusion chromatography
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size 25 μg
Transport Information
Supplemental Information
Specifications

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