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Qiagen 凯杰 Biosharp Omega

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Anti-CD2 (human), FITC, clone RPA-2.10

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货号：MABF1763

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB M Ascites Monoclonal Antibody
Description
Catalogue Number MAB1763
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Fibulin-3 Antibody
Alternate Names
  • EFEMP1
Background Information Fibulin-3 is a protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels and the gene that encodes fibulin 3 is EFEMP1. It is a secreted protein that is present in serum, urine and tissue samples. A single mutation in FBLN3 is responsible for an autosomal dominant form of macular degeneration (Marmorstein, et al., 2002)
References
Product Information
Format Ascites
Control
  • Positive: ARPE-19 cell line.
Presentation Ascites containg no preservatives.
Applications
Application This Anti-Fibulin-3 Antibody is validated for use in WB for the detection of Fibulin-3.
Key Applications
  • Western Blotting
Application Notes Western blot: 1:100 after immunoprecipitation
Biological Information
Immunogen GST-tagged fibulin-3 fusion protein containing amino acids 107-493.
Epitope amino acids 107-493
Clone G3-5
Host Mouse
Specificity Clone G3-5 recognizes human fibulin-3 with a MW of 55 kDa.
Isotype IgG1
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
Gene Symbol
  • EFEMP1
  • FBNL
  • MLVT
  • FBLN3
  • FLJ35535
  • DRAD
  • fibrillin-like
  • Fibulin-3
  • S1-5
  • FIBL-3
  • MGC111353
  • DHRD
  • MTLV
UniProt Number
UniProt Summary SIZE: 493 amino acids; 54641 Da
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: Q12805 # Defects in EFEMP1 are a cause of Doyne honeycomb retinal dystrophy (DHRD) [MIM:126600]; also known as malattia leventinese (MLVT OR ML). DHRD is an autosomal dominant disease characterized by yellow-white deposits known as drusen that accumulate beneath the retinal pigment epithelium.
SIMILARITY: SwissProt: Q12805 ## Belongs to the fibulin family. & Contains 6 EGF-like domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C for up to 12 months from date of receipt in undiluted aliquots. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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