Anti-CD3 (human), PE-Cy7, clone UCHT1

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Anti-CD3 (human), PE-Cy7, clone UCHT1

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货号：MABF1751

品牌：Millipore 密理博

配送至：

北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IHC	Rb	Unpurified	Monoclonal Antibody

Description
Catalogue Number	MABF751
Description	Anti-PF4, clone EPR7763, Rabbit Monoclonal Antibody
Alternate Names	Platelet factor 4 PF-4 C-X-C motif chemokine 4 Iroplact Oncostatin-A PF4 CXCL4 SCYB4
Background Information	Platelet factor 4 (PF-4), also known as C-X-C motif chemokine 4 or Iroplact or Oncostatin-A , and encoded by the gene name PF4 or CXCL4 or SCYB4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

References

Product Information
Format	Unpurified
Presentation	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

Applications
Application	This Anti-PF4 antibody is validated for use in WB, IH for the detection of PF4.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected PF4 in human spleen tissue. Produced in collaboration with Epitomics™

Biological Information
Immunogen	Synthetic peptide corresponding to human PF4.
Clone	EPR7763
Concentration	Please refer to lot specific datasheet.
Host	Rabbit
Specificity	Equilibrium disassociation constant (KD) is 5.40 x 10 -11 M
Isotype	IgG
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Gene Symbol	PF4 CXCL4 SCYB4
Purification Method	Unpurified
UniProt Number	P02776
Molecular Weight	~11 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in human spleen and human platelet tissue lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected PF4 in human spleen and human platelet tissue lysates.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Storage and Shipping Information

Storage Conditions

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.