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Rat X CRMP-5

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号:MAB5442

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
B, H, R WB, IHC R Culture Supernatant Monoclonal Antibody
Description
Catalogue Number MAB5442
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Collapsin Response Mediated Protein 5 Antibody, clone CR-1
Alternate Names
  • CRMP5
  • DRP-5
  • ULIP-6
  • CRAM
References
Product Information
Format Culture Supernatant
Presentation Unpurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL.
Applications
Application Anti-Collapsin Response Mediated Protein 5 Antibody, clone CR-1 detects level of Collapsin Response Mediated Protein 5 & has been published & validated for use in WB, IH.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application Notes Western blot: 1:500-1:2,000 on human and rat brain extracts. 1:500-1:2,000 on human small-cell lung carcinoma. 1:1,500-1:6,000 on bovine retina and optic nerve extracts.

Immunohistochemistry: 1:50-1:200 on bovine retina frozen sections fixed with 10% formalin. No reactivity on mouse cerebellum.

Protein isolation: Bound to Bio-Rad's Affi-gel (cat# 153-6046) to pull out native CRMP-5 from aqueous extracts of brain.

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen CRMP-5 purified from rat and human brain.
Clone CR-1
Host Rat
Specificity Collapsin response mediated protein-5 (CRMP-5). The antibody binds to a region of the human protein from between ~369 to 564 amino acids.
Isotype IgG1
Species Reactivity
  • Bovine
  • Human
  • Rat
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.[supplied by OMIM]
Gene Symbol
  • DPYSL5
  • CRAM
  • CRMP5
  • ULIP6
  • Ulip6
  • FLJ45383
  • DRP-5
  • CRMP-5
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q9BPU6 # May have a function in neuronal differentiation and/or axon growth.
SIZE: 564 amino acids; 61421 Da
SUBCELLULAR LOCATION: Cytoplasm (Potential).
SIMILARITY: SwissProt: Q9BPU6 ## Belongs to the dehydropyrimidinase family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Uses of the CR-1 and CR-3 antibodies are covered under pending patent application(s) assigned to the Mayo Foundation for Medical Education and Research (MFMER) and are proprietary to MFMER. Academic not-for-profit research institutions are granted an automatic license with the purchase of this product to use the antibody only for internal, non-sponsored, non-commercial, academic research purposes which license specifically excludes the right to sell, or otherwise transfer the antibody or its derivatives to third parties. In accepting this license, all users acknowledge that the CR-1 and CR-3 antibodies are experimental in nature. MFMER makes no warranties, express or implied of any kind, and hereby disclaims any warranties, representations, or guarantees of any kind as to the CR-1 and CR-3 antibodies, patents or product. All others are invited to request a license from MFMER prior to purchasing this antibody or using it for any purpose. For license information, please contact Mayo Medical Ventures, Office of Technology Commercialization at (507) 284-8878.
Packaging Information
Material Size 500 µL
Transport Information
Supplemental Information
Specifications

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