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Rb X Nerve Growth Factor-beta

市场价：: 0.00

促销价：: ¥0.00

货号：AB1526SP

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
Ch, H, M, R	ELISA, WB, IHC, FUNC	Rb	Purified	Polyclonal Antibody

Description
Catalogue Number	AB1526SP
Replaces	04-1119
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Nerve Growth Factor-β Antibody
Alternate Names	NGFbeta

References

Product Information
Format	Purified
Presentation	Purified immunoglobulin. Lyophilized from PBS. Contains no preservative. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).

Applications
Application	Anti-Nerve Growth Factor-β Antibody detects level of Nerve Growth Factor-β & has been published & validated for use in ELISA, WB, IH.
Key Applications	ELISA Western Blotting Immunohistochemistry Affects Function
Application Notes	Immunohistochemistry: 1-2 μg/mL (see suggested protocol). Immunoblotting: 1-2 μg/mL Inhibition of biological activity: 1-2 μg/mL BIOLOGICAL ACTIVITY: This antibody will completely inhibit the survival and neurite outgrowth actions of mouse NGF in chicken dorsal root ganglion neurons in vitro. ELISA: 1-2 μg/mL Use neat for in vivo animal studies. Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Mouse nerve growth factor-beta purified from salivary glands.
Host	Rabbit
Specificity	Nerve growth factor-beta (NGF). Less than 1% cross-reactivity with recombinant human NT3, NT4 and BDNF by ELISA.
Species Reactivity	Chicken Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_002506.2
Entrez Gene Summary	This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Gene Symbol	NGFB MGC161426 HSAN5 NGF Beta-NGF MGC161428
Non-Reactive Species	Bovine
UniProt Number	P01138
UniProt Summary	FUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SIZE: 241 amino acids; 26959 Da SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Secreted. DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable. SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain at -20 to -70°C in undiluted aliquots for up to one year after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. Glycerol (1:1) may be added for additional stability. Avoid repeated freeze/thaw cycles.

Packaging Information
Material Size	500 µg

Transport Information

Supplemental Information

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