Goat Anti-Calretinin Polyclonal Antibody - 炼石商城

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Goat Anti-Calretinin Polyclonal Antibody

市场价：: 0.00

促销价：: ¥0.00

货号：AB1550

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
Gp, H, M, R	IHC, WB	Gt	Serum	Polyclonal Antibody

Description
Catalogue Number	AB1550
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Calretinin Antibody

References

Product Information
Format	Serum
Control	Rat brain cortex, Mesothelioma tissue
Presentation	UnPurified goat Serum containing no preservatives.

Applications
Application	Detect Calretinin using this Anti-Calretinin Antibody validated for use in IH & WB.
Key Applications	Immunohistochemistry Western Blotting
Application Notes	Western blot at 1:10,000. Immunohistochemistry: IFA at 1:2,500, PAP at 1:2,500 (48 hours at +4 C). Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Rat calretinin.
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Goat
Specificity	Recognizes Calretinin.
Species Reactivity	Guinea Pig Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_001740.3 NM_007087.2 NM_007088.2
Entrez Gene Summary	Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin 2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin 1. Calbindin 2 contains five presumably active and one presumably inactive calcium-binding domains. Comparison with the partial sequences available for chick and guinea pig calbindin 2 reveals that the protein is highly conserved in evolution. The calbindin 2 message was detected in the brain, while absent from heart muscle, kidney, liver, lung, spleen, stomach and thyroid gland. There are two additional forms of alternatively spliced calbindin 2 mRNAs encoding C-terminally truncated proteins. Exon 7 can splice to exon 9, resulting in a frame shift and a translational stop at the second codon of exon 9, and encoding calretinin-20k. Exon 7 can also splice to exon 10, resulting in a frame shift and a translational stop at codon 15 of exon 10, and encoding calretinin-22k. The truncated proteins are able to bind calcium.
Gene Symbol	CALB2 Calretinin CAB29 CR CAL2
Purification Method	Unpurified
UniProt Number	P22676
UniProt Summary	FUNCTION: SwissProt: P22676 # Calretinin is a calcium-binding protein which is abundant in auditory neurons. SIZE: 271 amino acids; 31540 Da TISSUE SPECIFICITY: Brain. SIMILARITY: SwissProt: P22676 ## Belongs to the calbindin family. & Contains 6 EF-hand domains.
Molecular Weight	31.4 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

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