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Rb X Dopa Decarboxylase

市场价：: 0.00

促销价：: ¥0.00

货号：AB1569

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
B, Ca, Gp, H, R, Sh	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB1569
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Dopa Decarboxylase Antibody

References

Product Information
Format	Affinity Purified
Presentation	Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Applications
Application	Detect Dopa Decarboxylase using this Anti-Dopa Decarboxylase Antibody validated for use in IH & WB.
Key Applications	Immunohistochemistry Western Blotting
Application Notes	Immunoblotting: 1:500-1:1,000 Immunohistochemistry using formaldehyde-fixed brain sections. Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies.
Host	Rabbit
Specificity	DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot.
Species Reactivity	Bovine Canine Guinea Pig Human Rat Sheep
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_000790.3 NM_001082971.1
Gene Symbol	DDC AADC EC 4.1.1.28
UniProt Number	P20711
UniProt Summary	FUNCTION: SwissProt: P20711 # Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. COFACTOR: Pyridoxal phosphate. SIZE: 480 amino acids; 53894 Da SUBUNIT: Homodimer. DISEASE: SwissProt: P20711 # Defects in DDC are the cause of aromatic-L-amino-acid decarboxylase deficiency (AADC deficiency) [MIM:608643]. AADC deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive. SIMILARITY: SwissProt: P20711 ## Belongs to the group II decarboxylase family.

Physicochemical Information

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Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.

Packaging Information
Material Size	100 µL

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Supplemental Information

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