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Chk X Transferrin

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货号：AB3487

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H ELISA, WB Ch Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB3487
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Transferrin Antibody
References
Product Information
Format Affinity Purified
Presentation Liquid in PBS, pH 7.2 containing 0.02 % sodium azide.
Applications
Application Anti-Transferrin Antibody detects level of Transferrin & has been published & validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application Notes Western blot: 1:1,000-1:2,000

ELISA, direct: 0.1 μg/mL

It is expected that the antibody will also work for immunocytochemistry and immunohistochemistry. Specific reactivity has not been confirmed.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Human Transferrin, full length protein.
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Chicken
Specificity Transferrin
Species Reactivity
  • Human
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene is a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds 1 ion of ferric iron. The function of this encoded protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.
Gene Symbol
  • TF
  • PRO1557
  • PRO2086
  • DKFZp781D0156
  • ORFNames=PRO1400
  • transferrin
  • Transferrin
  • Siderophilin
UniProt Number
UniProt Summary FUNCTION: SwissProt: P02787 # Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
SIZE: 698 amino acids; 77050 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.
DISEASE:SwissProt: P02787 # Defects in TF are the cause of atransferrinemia [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
SIMILARITY: SwissProt: P02787 ## Belongs to the transferrin family. & Contains 2 peptidase S60 domains.
MISCELLANEOUS: The peptidase S60 domains do not have protease function as the catalytic residues are missing.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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