Ms X Integrin alpha4 Alexa Fluor® 488 Conjugated - 炼石商城

您好！欢迎来到炼石商城请登录注册兼职小伙伴

我的购物车

0

Qiagen 凯杰 Biosharp Omega

全部商品分类

小伙伴店铺

客服热线 0771-3293894

首页抗体Millipore 密理博>

图片仅供参考，请以实物为准

收藏

Ms X Integrin alpha4 Alexa Fluor® 488 Conjugated

市场价：: 0.00

促销价：: ¥0.00

货号：MAB16983X

品牌：Millipore 密理博

配送至：

北京朝阳

支付：账期货到付款

数量：

EA (预计3-5工作日到货)

亲，想了解价格请QQ咨询客服！

工作时间

周一至周五：9:00-18:00

咨询电话

0771-3293894

在线咨询

: 客服郭恒蔡玉坤曾宪飞技术咨询

浏览了该商品的用户最终购买

RNeasy Mini Kit (50) 50次

RNeasy Mini Kit (50) 50次

3720.00

Plasmid Mini Kit I(200) 200次

Plasmid Mini Kit I(200) 200...

576.00

10ul吸头，透明，袋装，可灭菌 1000支/袋，50袋/箱

10ul吸头，透明，袋装，可灭菌...

85.80

浏览了该商品的用户还浏览了

QIAfilter Plasmid Maxi Kit (10) -10

QIAfilter Plasmid Maxi Kit (...

3000.00

QIAamp DNA Blood Midi Kit (20) 20次

QIAamp DNA Blood Midi Kit (2...

2680.00

QIAamp UCP Pathogen Mini Kit (50)

QIAamp UCP Pathogen Mini Kit...

4112.00

商品介绍
商品咨询

Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, Pm	ELISA, FC, ICC, IHC, IP, FUNC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB16983Z
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Integrin α4 Antibody, clone P1H4, azide free
Alternate Names	CD49d MAB16983

References

Product Information
Format	Purified
Control	Widely expressed, Intestinal mucosa
Presentation	Protein A Purified immunoglobulin in 0.01M PBS pH 7.1, 0.15M NaCl containing no preservatives.

Applications
Application	Anti-Integrin α4 Antibody, clone P1H4, azide free is an antibody against Integrin α4 for use in ELISA, FC, IC, IH & IP.
Key Applications	ELISA Flow Cytometry Immunocytochemistry Immunohistochemistry Immunoprecipitation Affects Function
Application Notes	Immunohistochemistry (preferred fixatives are acetone and alcohols) Immunocytochemistry Immunoprecipitation FACS Analysis ELISA Radioimmunoassay Biological Activity: MAB16983Z inhibits CS-1 and VCAM binding. Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Human T lymphocytes
Clone	P1H4
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits Monoclonal antibody MAB16983Z was produced by immunization with human T lymphocytes. The antibody is reactive with integrin alpha-4 from primate and human species.
Isotype	IgG1
Species Reactivity	Human Primate
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_000632.3
Entrez Gene Summary	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Some integrin alpha M proteins contain an inserted amino acid (Q, between AA positions 499 and 500) resulting from a 3bp shift in a splice acceptor that inserts the codon CAG; receptors with or without the extra amino acid are functionally indistinguishable
Gene Symbol	ITGAM MO1A CD11b CR3A MAC1A CD11B MGC117044 MAC-1
Purification Method	Protein A Purfied
UniProt Number	P11215
UniProt Summary	FUNCTION: SwissProt: P11215 # Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. SIZE: 1152 amino acids; 127179 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Predominantly expressed in monocytes and granulocytes. DOMAIN: SwissProt: P11215 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

登录 / 注册

购物指南免费注册批量采购购物流程购物保障

配送方式上门自提第三方配送炼石配送

支付方式货到付款账期付款

售后服务售后政策退款说明售后流程免责条款

服务热线

0771-3293894