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Ms X Integrin b6

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货号：MAB2076Z

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, Mk, R, Rb FC, IP, ICC, IHC M Purified Monoclonal Antibody
Description
Catalogue Number MAB2076Z
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Integrin β6 Antibody, clone CSβ6, azide free
Alternate Names
  • MAB2076
References
Product Information
Format Purified
Presentation Sterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives.
Applications
Application Anti-Integrin β6 Antibody, clone CSβ6, azide free detects level of Integrin β6 & has been published & validated for use in FC, IP, IC, IH.
Key Applications
  • Flow Cytometry
  • Immunoprecipitation
  • Immunocytochemistry
  • Immunohistochemistry
Application Notes Immunohistochemistry (acetone fixation): Effective for Rabbit, rat, monkey, and human. Not effective for mouse tissue.

Immunocytochemistry: Effective for F6, HT-29, H441 cell lines (others not tested).

Flow cytometry: Effective for all species tested, including rabbit, rat, monkey, human, and mouse.

Immunoprecipitation

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen beta 6 knockout mice have been immunized with recombinant secreted human alpaVbeta6.
Clone CSbeta6
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Monoclonal antibody MAB2076Z, raised by immunizing beta6 knockout mice with recombinant secreted human alphavbeta6, is useful for flow cytometry and immunoprecipitation in all species tested, including mouse. It also works well for immunohistochemistry of acetone-fixed tissues in several species, including rat, rabbit, monkey, and human. The antibody does not work well for immunohistochemistry of mouse tissue. This antibody does not recognize the aV subunit and does not react with alphaV integrins other than alphavbeta6. Because the antibody is not effective in western blot, it is unknown whether the epitope recognized by the antibody localizes to the alphavbeta6 heterodimer or to the beta6 subunit only.
Isotype IgG1
Species Reactivity
  • Human
  • Monkey
  • Rat
  • Rabbit
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ITGB6
Non-Reactive Species
  • Mouse
UniProt Number
UniProt Summary FUNCTION: SwissProt: P18564 # Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands.
SIZE: 788 amino acids; 85936 Da
SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P18564 ## Belongs to the integrin beta chain family. & Contains 1 VWFA domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at 2-8°C.
Packaging Information
Material Size 100 µg
Transport Information
Supplemental Information
Specifications

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