Anti-Integrin a9b1, clone Y9A2, azide free - 炼石商城

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Anti-Integrin a9b1, clone Y9A2, azide free

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货号：MAB2078Z

品牌：Millipore 密理博

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
Gp, H	FC, IP, FUNC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB2078Z
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Integrin α9β1 Antibody, clone Y9A2, azide free
Alternate Names	MAB2078

References

Product Information
Format	Purified
Control	Integrin alpha9beta1 positive tissues include basal keratinocytes, hepatocytes, muscle (smooth and skeletal), and airway epithelium.
Presentation	Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.

Applications
Application	Detect Integrin α9β1 using this Anti-Integrin α9β1 Antibody, clone Y9A2, azide free validated for use in FC & IP.
Key Applications	Flow Cytometry Immunoprecipitation Affects Function
Applications Not Recommended	Western Blotting Immunohistochemistry
Application Notes	Immunoprecipitation FACS Analysis Function blocking: 100% inhibition of alpha9beta1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10 μg/mL. Not effective for immunohistochemistry, immunocytochemistry or western blot. Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Murine L cells transfected with human alpha9.
Clone	Y9A2
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Reactive with human and guinea pig alpha9beta1.
Isotype	IgG1
Species Reactivity	Guinea Pig Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_002207.2
Entrez Gene Summary	This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Gene Symbol	ITGA9 RLC ALPHA-RLC ITGA4L
Non-Reactive Species	Rat
Purification Method	Protein A Purfied
UniProt Number	Q13797
UniProt Summary	FUNCTION: SwissProt: Q13797 # Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin. SIZE: 1035 amino acids; 114561 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-9 associates with beta-1. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers. SIMILARITY: SwissProt: Q13797 ## Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats.

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Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	100 µg

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