[关闭]
您好！欢迎来到炼石商城   请登录  注册    兼职小伙伴  
我的购物车
0
Qiagen 凯杰 Biosharp Omega

首页抗体Millipore 密理博>

图片仅供参考，请以实物为准
收藏

Ms X Hsp60

市场价：
0.00
促销价：
¥0.00

货号：MAB3514

品牌：Millipore 密理博

配送至：

支付： 账期 货到付款

数量：

EA (预计3-5工作日到货)

亲，想了解价格请QQ咨询客服！

工作时间

周一至周五：9:00-18:00

咨询电话

0771-3293894

在线咨询

客服 郭恒 蔡玉坤 曾宪飞 技术咨询

浏览了该商品的用户最终购买

RNeasy Mini Kit (50) 50次
RNeasy Mini Kit (50) 50次
3720.00
Plasmid Mini Kit I(200) 200次
Plasmid Mini Kit I(200) 200...
576.00
10ul吸头，透明，袋装，可灭菌 1000支/袋，50袋/箱
10ul吸头，透明，袋装，可灭菌...
85.80

浏览了该商品的用户还浏览了

QIAfilter Plasmid Maxi Kit (10) -10
QIAfilter Plasmid Maxi Kit (...
3000.00
QIAamp DNA Blood Midi Kit (20) 20次
QIAamp DNA Blood Midi Kit (2...
2680.00
QIAamp UCP Pathogen Mini Kit (50)
QIAamp UCP Pathogen Mini Kit...
4112.00
Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
Ch, H, Ht, M, R IP, WB, ICC, IHC, IH(P) M Purified Monoclonal Antibody
Description
Catalogue Number MAB3514
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Heat Shock Protein 60 Antibody, a.a. 383-447, clone LK1
Alternate Names
  • HSP60
References
Product Information
Format Purified
Control
  • POSITIVE CONTROL:

    BT474, MAD109, RenCa, SK-NEP-1, U937 cells or breast carcinoma.
Presentation Liquid in 10 mM PBS, pH 7.4 with 0.2% BSA and 15 mM sodium azide.
Applications
Application Anti-Heat Shock Protein 60 Antibody, a.a. 383-447, clone LK1 detects level of Heat Shock Protein 60 & has been published & validated for use in IP, WB, IC, IH, IH(P).
Key Applications
  • Immunoprecipitation
  • Western Blotting
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunohistochemistry (Paraffin)
Application Notes Immunoblotting: 1-2 μg/mL

Immunohistochemistry (frozen and formalin/paraffin): 1-2 μg/mL. Staining of formalin fixed tissue sections requires boiling the tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes.

Immunocytochemistry

Electron Microscopy (Boog et al., 1992).

Immunoprecipitation (Native and denatured): 2 μg antibody/mg of protein lystate using Protein G.

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen Recombinant hsp60 protein (Boog et al., 1992).
Epitope a.a. 383-447
Clone LK1
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Reacts a 60 kDa protein identified as heat shock protein 60 (hsp60) (Boog et al., 1992). The epitope recognized by MAB3514 is located between amino acids 383-447 of human hsp60 (Boog et al., 1992).

CELLULAR LOCALIZATION:

Cytoplasmic.
Isotype IgG1
Species Reactivity
  • Chicken
  • Human
  • Hamster
  • Mouse
  • Rat
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Gene Symbol
  • HSPD1
  • HuCHA60
  • chaperonin
  • CPN60
  • SPG13
  • HSP65
  • Hsp60
  • GROEL
  • HSP-60
  • HSP60
UniProt Number
UniProt Summary FUNCTION: SwissProt: P10809 # Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
SIZE: 573 amino acids; 61055 Da
SUBUNIT: Interacts with HBV protein X.
SUBCELLULAR LOCATION: Mitochondrion matrix.
DISEASE: SwissProt: P10809 # Defects in HSPD1 are a cause of spastic paraplegia type 13 (SPG13) [MIM:605280]. SPG13 is a form of autosomal dominant hereditary spastic paraplegia (AD-HSP). HSP is a group of inherited degenerative spinal cord disorders characterized by a slow, gradual, progressive weakness and spasticity (stiffness) of the legs. Rate of progression and the severity of symptoms is quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body.
SIMILARITY: SwissProt: P10809 ## Belongs to the chaperonin (HSP60) family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Packaging Information
Material Size 500 µL
Transport Information
Supplemental Information
Specifications

温馨提示:因厂家更改产品包装、产地或者更换随机附件等没有任何提前通知，且每位咨询者购买情况、提问时间等不同，为此以下回复仅对提问者3天内有效，其他网友仅供参考！若由此给您带来不便请多多谅解，谢谢！

我要咨询

咨询内容：
购物指南 免费注册 批量采购 购物流程 购物保障
配送方式 上门自提 第三方配送 炼石配送
支付方式 货到付款 账期付款
售后服务 售后政策 退款说明 售后流程 免责条款

服务热线

0771-3293894

关于我们|帮助中心|诚聘英才|炼石云实验室|联系我们|友情链接

Copyright 2014-2025 炼石云商网络科技（海南）有限公司版权所有 琼ICP备2023006525号-3