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Sh X Chx10N-Terminal

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货号：AB9016

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
B, H, M, R WB Sh Purified Polyclonal Antibody
Description
Catalogue Number AB9016
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Chx10 Antibody, NT
Alternate Names
  • Hox-10
  • Ocular Retardation
  • C. Elegans ceh-10 Homeo Domain Containing Homolog
References
Product Information
Format Purified
Presentation Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.
Applications
Application Detect Chx10 using this Anti-Chx10 Antibody, N-terminus validated for use in WB.
Key Applications
  • Western Blotting
Application Notes Immunoblotting: 0.5-1.0 μg/mL. Reacts with the 46 kD protein in rat and mouse retinal tissue lysate.

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Recombinant human Chx10 protein, N-terminal.
Epitope N-terminus
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Sheep
Specificity Chx10
Species Reactivity
  • Bovine
  • Human
  • Mouse
  • Rat
Antibody Type Polyclonal Antibody
Entrez Gene Number
Gene Symbol
  • VSX2
  • HOX10
  • MCOPCB3
  • CHX10
  • MCOP2
  • RET1
UniProt Number
UniProt Summary FUNCTION: SwissProt: P58304 # Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity).
SIZE: 361 amino acids; 39411 Da
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.
DISEASE: SwissProt: P58304 # Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities [MIM:610092]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. It is a cause of congenital blindness. & Defects in VSX2 are the cause of isolated microphthalmia with coloboma 3 (MCOPCB3) [MIM:610092]; also known as isolated colobomatous microphthalmia 3. & Defects in VSX2 are the cause of isolated microphthalmia 2 (MCOP2) [MIM:610093]; also known as clinical anophthalmia.
SIMILARITY: SwissProt: P58304 ## Belongs to the paired homeobox family. & Contains 1 CVC domain. & Contains 1 homeobox DNA-binding domain. & Contains 1 OAR domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 250 µg
Transport Information
Supplemental Information
Specifications

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