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Rb X DopamineTransporter

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号:AB5802

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H, Mk IHC, WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number AB5802
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Dopamine Transporter Antibody, extracellular Loop 2
References
Product Information
Format Affinity Purified
Presentation Affinity purified immunoglobulin. Each vial contains ~33 μg of affinity-purified antibody in 100 μL of 10 mM HEPES (pH 7.5), 150 mM NaCl with 100 μg/mL BSA and 50% glycerol.
Applications
Application Anti-Dopamine Transporter Antibody, extracellular Loop 2 is an antibody against Dopamine Transporter for use in IH & WB.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application Notes Immunoblotting: 1:500-1:1,000

Immunohistochemistry using formaldehyde-fixed brain sections: 1:500-1:1,000

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Synthetic peptide from the EL2 region of human dopamine transporter.
Epitope extracellular Loop 2
Host Rabbit
Specificity Dopamine Transporter, Extracellular loop 2 (EL2).
Species Reactivity
  • Human
  • Monkey
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The dopamine transporter (DAT1) mediates the active reuptake of dopamine from the synapse and is a principal regulator of dopaminergic neurotransmission. The DAT1 gene has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse (Vandenbergh et al., 1992 [PubMed 1359373]).[supplied by OMIM]
Gene Symbol
  • SLC6A3
  • ADHD
  • DAT
  • DAT1
  • ADD
UniProt Number
UniProt Summary FUNCTION: SwissProt: Q01959 # Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
SIZE: 620 amino acids; 68495 Da
SUBUNIT: Homooligomer; disulfide-linked. Interacts with PRKCABP and TGFB1I1.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: Q01959 ## Belongs to the sodium:neurotransmitter symporter (SNF) family.
MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20 to -80°C in undiluted aliquots for up to six months. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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