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Ms X RAD51D

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货号：MAB3698

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H WB M Ascites Monoclonal Antibody
Description
Catalogue Number MAB3698
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Rad51D Antibody, clone 5B3
References
Product Information
Format Ascites
Presentation Ascites fluid. Liquid. Contains no preservative.
Applications
Application Detect Rad51D with Anti-Rad51D Antibody, clone 5B3 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Key Applications
  • Western Blotting
Application Notes Western blot

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Recombinant human Rad51D
Clone 5B3
Host Mouse
Specificity Rad51D. No cross reactivity with Rad51B, Rad51C, XRCC2 or XRCC3 by Western blot.
Isotype IgG1
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Several alternatively spliced transcript variants of this gene have been described, but the biological validity of some of them has not been determined.
Gene Symbol
  • RAD51L3
  • R51H3
  • Trad
  • TRAD
  • HsTRAD
  • RAD51D
UniProt Number
UniProt Summary FUNCTION: SwissProt: O75771 # Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
SIZE: 328 amino acids; 35049 Da
SUBUNIT: Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. Interacts with ZSWIM7.
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.
SIMILARITY: SwissProt: O75771 ## Belongs to the recA family. RAD51 subfamily.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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