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Rb Anti-Homocysteine

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货号：AB5512

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R ELISA Rb Serum Polyclonal Antibody
Description
Catalogue Number AB5512
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Homocysteine Antibody
Background Information Homocysteine a sulphur containing amino acid, is formed by the transmethylation of methionine, an essential amino acid. Homocysteine may be irreversibly metabolised to cystathionine by cystathionine synthetase. This reaction uses pyridoxal phosphate (Vitamin B6) as a co-enzyme (see figure). The enzyme cystathionine synthetase is deficient in homocysteinuria, a rare genetic disease associated with high blood levels of homocysteine and the development of premature atherosclerosis. This and the association of other rare enzyme deficiencies with homocysteinemia and premature atherosclerosis led McCully to formulate the homocysteine hypothesis of atherosclerosis (McCully KS, The homocysteine theory of atherosclerosis. Atherosclerosis. 1976; 20: 23-27)
References
Product Information
Format Serum
Presentation Rabbit antiserum. Liquid with 0.05% sodium azide.
Applications
Application This Anti-Homocysteine Antibody is validated for use in ELISA for the detection of Homocysteine.
Key Applications
  • ELISA
Application Notes Suggested working dilution: 1:1,000-1:5,000

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen Homocysteine-Glutaraldehyde-BSA
Host Rabbit
Specificity Homocysteine



The cross-reactivities were determined using an ELISA test by competition experiments with the following compounds:



Compound Cross-reactivity ratio

Homocysteine-G-BSA 1

Cysteine-G-BSA 1/450

Homocysteic acid-G-BSA 1/>100,000



Abbreviations:



(G) Glutaraldehyde

(BSA) Bovine Serum Albumin
Species Reactivity
  • Rat
Antibody Type Polyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size 100 µL
Transport Information
Supplemental Information
Specifications

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