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Ms X Hu CD31 PE

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号:CBL468P

牌:Millipore 密理博

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Replacement Information

重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H FC M Phycoerythrin Monoclonal Antibody
Description
Catalogue Number CBL468P
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-PECAM-1 Antibody, clone HC1/6, Phycoerythrin conjugated
Alternate Names
  • CD31
References
Product Information
Format Phycoerythrin
Presentation The conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
Applications
Application Anti-PECAM-1 Antibody, clone HC1/6, Phycoerythrin conjugated detects level of PECAM-1 & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Application Notes Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis

Suitable for direct staining in flow cytometry

Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen PMA - treated U937 cells
Clone HC1/6
Host Mouse
Specificity The antibody reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.

FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Isotype IgG1
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PECAM1
  • EndoCAM
  • GPIIA
  • PECAM-1
  • CD31
  • CD31/EndoCAM
UniProt Number
UniProt Summary FUNCTION: SwissProt: P16284 # This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
SIZE: 738 amino acids; 82536 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
PTM: Phosphorylated on Ser and Tyr residues after cellular activation.
SIMILARITY: SwissProt: P16284 ## Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.
Packaging Information
Material Size 100 assays
Transport Information
Supplemental Information
Specifications

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