Anti-CD34 Class II, cln QBEND/10, FITC Conj (100 assays) - 炼石商城

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Anti-CD34 Class II, cln QBEND/10, FITC Conj (100 assays)

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货号：CBL496F

品牌：Millipore 密理博

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北京朝阳

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, Mk	FC	M	FITC	Monoclonal Antibody

Description
Catalogue Number	CBL496F
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-CD34 Class II Antibody, clone QBEND/10, FITC conjugated

References

Product Information
Format	FITC
Presentation	The conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.

Applications
Application	This Anti-CD34 Antibody (Class II), clone QBEND/10, FITC conjugated is validated for use in FC for the detection of CD34 Class II.
Key Applications	Flow Cytometry
Application Notes	Identification of haemopoietic progenitor cells Studies into the control mechanisms of early haemopoiesis Purification of haemopoietic cells from, for example, FACS The antibody reacts with both frozen and fixed tissue sections from vascular endothelium and stromal fibroblasts Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Human endothelial vesicles
Clone	QBEND/10
Host	Mouse
Specificity	The antibody recognizes a heavily glycosylated transmembrane protein: gp 105-120 kDa. The antigen is expressed on immature human haemopoietic precursor cells, capillary endothelial cells and human myeloid cells in the following categories: subsets of CFU-GEMM and BFU-E, all CFU-GM, granulocyte precursors, monocytes, myeloid leukaemias. This antibody recognizes the class II epitope showing resistance to neuraminidase enzyme cleavage. FUSION PARTNER: NSO myeloma cell line
Isotype	IgG1
Species Reactivity	Human Monkey
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_001025109.1 NM_001773.2
Entrez Gene Summary	CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM]
Gene Symbol	CD34
UniProt Number	P28906
UniProt Summary	FUNCTION: SwissProt: P28906 # Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. SIZE: 385 amino acids; 40716 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. DEVELOPMENTAL STAGE: On early hematopoietic progenitor cells. PTM: Highly glycosylated. & Phosphorylated on serine residues by PKC. DISEASE:SwissProt: P28906 # Abnormal CD34 expression in leukemogenesis. SIMILARITY: SwissProt: P28906 ## Belongs to the CD34 family.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Availability by Geography	This product is not available for sale in the United States.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.

Packaging Information
Material Size	100 assays

Transport Information

Supplemental Information

Specifications

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