Anti-Na beta2 (Rb Polyclonal) - 炼石商城

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Anti-Na beta2 (Rb Polyclonal)

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促销价：: ¥0.00

货号：AB5358-200UL

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
R	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB5358-200UL
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Sodium Channel NaB2 Antibody
Alternate Names	B2 Subunit of Voltage-Gated Na+ Channel SCN2B

References

Product Information
Format	Affinity Purified
Control	CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
Presentation	Affinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA, and 0.05 % sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).

Applications
Application	Anti-Sodium Channel NaB2 Antibody detects level of Sodium Channel NaB2 & has been published & validated for use in IH & WB.
Key Applications	Immunohistochemistry Western Blotting
Application Notes	Western blotting: 1:200 on rat brain membranes. Immunohistochemistry on rat brain sections. Dilutions should be made using a carrier protein such as BSA (1-3%). Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Highly purified peptide corresponding to residues 197-215 of rat beta2 subunit of voltage-gated Na+ channels (Isom et al. 1995). Accession P54900. It is expected to work on human because the immunogen sequence is highly conserved (17/19 residues). Reactivity with other species has not yet been tested.
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	Recognizes Nab2. The epitope specific for Nab2 is not present in any other known proteins.
Species Reactivity	Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_004588.3
Gene Symbol	SCN2B ORFNames=UNQ326/PRO386
UniProt Number	O60939
UniProt Summary	FUNCTION: SwissProt: O60939 # Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity). SIZE: 215 amino acids; 24326 Da SUBUNIT: The sodium channel consists of a pore-forming alpha subunit, beta-1 and beta-2 subunits. Beta-1 is non-covalently associated with alpha, while beta-2 is covalently linked by disulfide bonds. Interaction with SCN10A and TNR (By similarity). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Brain specific. SIMILARITY: SwissProt: O60939 ## Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain lyophilized material at -20°C for up to 6 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Packaging Information
Material Size	200 µL

Transport Information

Supplemental Information

Specifications

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