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Rb X Neurturin

市场价：: 0.00

促销价：: ¥0.00

货号：AB5404

品牌：Millipore 密理博

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北京朝阳

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数量：

EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	IHC	Rb	Serum	Polyclonal Antibody

Description
Catalogue Number	AB5404
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Neurturin Antibody

References

Product Information
Format	Serum
Presentation	Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

Applications
Application	Anti-Neurturin Antibody detects level of Neurturin & has been published & validated for use in IH.
Key Applications	Immunohistochemistry
Application Notes	Immunohistochemistry: 1:1,000-1:2,000 Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Recombinant human Neurturin.
Host	Rabbit
Specificity	Neurturin. No cross reactivity with GDNF.
Species Reactivity	Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_004558.2
Entrez Gene Summary	Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.
Gene Symbol	NRTN NTN neurturin
UniProt Number	Q99748
UniProt Summary	FUNCTION: SwissProt: Q99748 # Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. SIZE: 197 amino acids; 22405 Da SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted. DISEASE: SwissProt: Q99748 # Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. SIMILARITY: SwissProt: Q99748 ## Belongs to the TGF-beta family. GDNF subfamily.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain lyophilized material at -20°C to -70°C for up to 6 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Packaging Information
Material Size	50 µL

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