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Rt X Hu C-Terminal Endothelin

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货号：CBL87

品牌：Millipore 密理博

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
H ICC R Purified Monoclonal Antibody
Description
Catalogue Number CBL87
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-Endothelin Antibody, CT, clone 3G10
References
Product Information
Format Purified
Control
  • Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Presentation The monoclonal is presented at in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Applications
Application This Anti-Endothelin Antibody, C-terminus, clone 3G10 is validated for use in IC for the detection of Endothelin.
Key Applications
  • Immunocytochemistry
Application Notes Development of IRMA assays for ET-1 (CBL 85) and ET-3 (CBL 86)

Suitable for immunocytochemistry on frozen sections

Optimal working dilutions must be determined by the end user.
Biological Information
Epitope C-terminus
Clone 3G10
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Rat
Specificity Recognizes the C-terminal region of all endothelins (amino acid residues 15-21) when used as a capture antibody in IRMA assays. The antibody does not cross-react with "big" endothelin.
Isotype IgG2b
Species Reactivity
  • Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • EDN1
  • OTTHUMP00000039245
  • Preproendothelin-1
  • ET1
  • PPET1
  • ET-1
  • HDLCQ7
Purification Method Protein A Purfied
UniProt Number
UniProt Summary FUNCTION: SwissProt: P05305 # Endothelins are endothelium-derived vasoconstrictor peptides.
SIZE: 212 amino acids; 24425 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
SIMILARITY: SwissProt: P05305 ## Belongs to the endothelin/sarafotoxin family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Packaging Information
Material Size 1 mg
Transport Information
Supplemental Information
Specifications

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