Anti-A2B5, clone A2B5-105 - 炼石商城

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Anti-A2B5, clone A2B5-105

市场价：: 0.00

促销价：: ¥0.00

货号：MAB312

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
Ma	FC, ICC, IF, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB312
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-A2B5 Antibody, clone A2B5-105
Alternate Names	Neuron Cell Surface Antigen

References

Product Information
Format	Purified
Control	Type II astrocytes, human neural progenitors
Presentation	Liquid in 0.02M PB, 0.25M NaCl, pH 7.6 containing 0.1% sodium azide.

Applications
Application	Detect A2B5 using this Anti-A2B5 Antibody, clone A2B5-105 validated for use in FC, IC, IF, IH.
Key Applications	Flow Cytometry Immunocytochemistry Immunofluorescence Immunohistochemistry
Application Notes	Indirect immunofluorescence (1:100 - 1:500) in the detection of neurons in tissue culture. Using double immunofluorescence the GQ ganglioside has a similar distribution on neurons to the D2 protein, to the tetanus toxin receptor and to neurofilaments (Walsh, 1980). May also be used in the depletion of neurons for a mixed population or their purification by affinity chromatography. May also be useful for detecting the metastatic spread of neuroblastoma cells into bone marrow. Flow cytometry: live cells {Maric, D. et al. (2000) Cerebral Cortex 10:729-747}. Immunohistochemistry: Frozen, fixed tissues (Levison & McCarthy, 1989) Complement-mediated cytotoxicity (Eisenbarth et al., 1979) Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Embryonic chicken retinal cells
Clone	A2B5-105
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Reacts with a surface antigen on neurons in the retina, brain, spinal cord and dorsal root ganglia, and with all tested human neuroblastoma cell lines. Does not seem to bind with any leukemic cell lines or with bone marrow cells from patients with leukemia, nor with cells from normal bone marrow. Cytotoxic to neurons in the presence of guinea-pig complement. Protein A binding is positive. Binds with GQ ganglioside on the plasma membrane of neurons of animals of all species tested to date (Eisenbarth, et al., 1979).
Isotype	IgM
Species Reactivity	Mammals
Antibody Type	Monoclonal Antibody
Gene Symbol	A2B5
Purification Method	Ammonium Sulfate Precipitation

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

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