Ms X Hu TIMP-3

您好！欢迎来到炼石商城请登录注册兼职小伙伴

我的购物车

Qiagen 凯杰 Biosharp Omega

客服热线 0771-3293894

首页抗体Millipore 密理博>

图片仅供参考，请以实物为准

市场价：: 0.00

促销价：: ¥0.00

货号：MAB3318

品牌：Millipore 密理博

配送至：

北京朝阳

支付：账期货到付款

数量：

EA (预计3-5工作日到货)

亲，想了解价格请QQ咨询客服！

工作时间

周一至周五：9:00-18:00

咨询电话

0771-3293894

在线咨询

: 客服郭恒蔡玉坤曾宪飞技术咨询

浏览了该商品的用户最终购买

RNeasy Mini Kit (50) 50次

3720.00

Plasmid Mini Kit I(200) 200...

576.00

10ul吸头，透明，袋装，可灭菌...

85.80

浏览了该商品的用户还浏览了

QIAfilter Plasmid Maxi Kit (...

3000.00

QIAamp DNA Blood Midi Kit (2...

2680.00

QIAamp UCP Pathogen Mini Kit...

4112.00

商品介绍
商品咨询

Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, Rb	IH(P), WB	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB3318
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-TIMP-3 Antibody, a.a. 170-188, clone 136-13H4
Alternate Names	Tissue Inhibitor of Metalloproteinase-3

References

Product Information
Format	Purified
Control	Breast carcinoma tissue
Presentation	Liquid in 0.1 M sodium phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.

Applications
Application	Anti-TIMP-3 Antibody, a.a. 170-188, clone 136-13H4 is an antibody against TIMP-3 for use in IH(P) & WB.
Key Applications	Immunohistochemistry (Paraffin) Western Blotting
Application Notes	Immunoblotting: 2 ug/mL Immunohistochemistry (Paraffin):10ug/mL Immunohistochemistry (Frozen): 2 ug/mL

Biological Information
Immunogen	Oligopeptide of SWYRGWAPPDKSIINATDP (residue 170-188) on human tissue inhibitor of metalloproteinases-3.
Epitope	a.a. 170-188
Clone	136-13H4
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Specifically reacts with human TIMP-3. This is a purified mouse monoclonal antibody to an oligopeptide of SWYRGWAPPDKSIINATDP (residue 170-188) on human tissue inhibitor of metalloproteinases-3 (human TIMP-3). MAB3318 cross-reacts with rabbit TIMP-3, but does not react with human TIMP-1 and human TIMP-2.
Isotype	IgG1κ
Species Reactivity	Human Rabbit
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_000362.4
Entrez Gene Summary	This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Gene Symbol	TIMP3 HSMRK222 K222 K222TA2 TIMP-3 SFD
Purification Method	Protein A Purfied
UniProt Number	P35625
UniProt Summary	FUNCTION: SwissProt: P35625 # Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. May form part of a tissue- specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. SIZE: 211 amino acids; 24145 Da SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix. DISEASE: SwissProt: P35625 # Defects in TIMP3 are the cause of Sorsby fundus dystrophy (SFD) [MIM:136900]. SFD is a rare autosomal dominant macular disorder with an age of onset in the fourth decade. It is characterized by loss of central vision from subretinal neovascularization and atrophy of the ocular tissues. Generally, macular disciform degeneration develops in the patients eye within 6 months to 6 years. SIMILARITY: SwissProt: P35625 ## Belongs to the protease inhibitor I35 (TIMP) family. & Contains 1 NTR domain.
Molecular Weight	26 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Availability by Geography	This product is not available for sale in Japan.
Usage Statement	Manufactured by Daiichi Fine Chemical Co., Ltd Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Product Usage Statements

Availability by Geography

This product is not available for sale in Japan.

Usage Statement

Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.