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Ms X Agrin

市场价：: 0.00

促销价：: ¥0.00

货号：MAB5204

品牌：Millipore 密理博

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北京朝阳

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数量：

EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
M, R	WB, ICC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB5204
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Agrin Antibody

References

Product Information
Format	Purified
Presentation	Purified immunoglobulin. Liquid in PBS containing 50% glycerol and 0.09% sodium azide.

Applications
Application	Anti-Agrin Antibody is an antibody against Agrin for use in WB & IC.
Key Applications	Western Blotting Immunocytochemistry
Application Notes	Immunocytochemistry: 10 μg/mL Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Recombinant rat agrin (C-terminal construct)
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	MAB5204 recognizes rat and mouse agrin. The epitope has been mapped near the splicing site Z. Binding of this antibody to agrin causes marked reduction in nAChR clusters.
Isotype	IgG1
Species Reactivity	Mouse Rat
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NM_198576.2
Entrez Gene Summary	Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction.[supplied by OMIM]
Gene Symbol	AGRN agrin OTTHUMP00000044043 FLJ45064 AGRIN
UniProt Number	O00468
UniProt Summary	FUNCTION: SwissProt: O00468 # Component of the basal lamina that causes the aggregation of acetylcholine receptors and acetylcholine-esterase on the surface of muscle fibers of the neuromuscular junction (By similarity). SIZE: 2045 amino acids; 214846 Da SUBUNIT: Binds to laminin. SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction (By similarity). PTM: Contains heparan sulfate chains as well as N-linked and O- linked oligosaccharides (By similarity). SIMILARITY: SwissProt: O00468 ## Contains 4 EGF-like domains. & Contains 9 Kazal-like domains. & Contains 2 laminin EGF-like domains. & Contains 3 laminin G-like domains. & Contains 1 NtA (N-terminal agrin) domain. & Contains 1 SEA domain.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain lyophilized at material -20°C or below for up to 12 months. After reconstitution maintain at -20°C to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Packaging Information
Material Size	200 µg

Transport Information

Supplemental Information

Specifications

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