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Ms X Serotonin Transporter

市场价：: 0.00

促销价：: ¥0.00

货号：MAB1564

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
R	IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MAB1564
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-Serotonin Transporter Antibody, clone 17-7A4

References

Product Information
Format	Purified
Control	Brain tissue
Presentation	Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.

Applications
Application	Detect Serotonin Transporter using this Anti-Serotonin Transporter Antibody, clone 17-7A4 validated for use in IH.
Key Applications	Immunohistochemistry
Application Notes	Immunohistochemistry: 0.5-1.0 μg/mL on paraformaldehyde fixed brain and adrenal tissue. Has not been tested on paraffin embedded tissue. Not recommended for use in Western blotting. Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Rat serotonin transporter, N-terminus/GST fusion protein (aa 1-85).
Clone	17-7A4
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Recognizes Serotonin Transporter.
Isotype	IgG1
Species Reactivity	Rat
Antibody Type	Monoclonal Antibody
Entrez Gene Summary	This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Gene Symbol	5HTT SC6A4 SLC6A4 HTT SERT
Purification Method	Protein A Purfied
UniProt Number	P31645 P31652
UniProt Summary	FUNCTION: SwissProt: P31645 # Terminates the action of serotonin by its high affinity sodium-dependent reuptake into presynaptic terminals. SIZE: 630 amino acids; 70325 Da SUBUNIT: Interacts with TGFB1I1. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. SIMILARITY: SwissProt: P31645 ## Belongs to the sodium:neurotransmitter symporter (SNF) family. MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

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